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Phase 2 Study Shows Promising Results for Potential Mucus Clearance Drug

A new drug intended to make it easier to clear mucus from the lungs of people with cystic fibrosis showed promising results in a Phase 2 clinical trial. The drug, called SPX-101, blocks the overactive sodium channels that line CF lung cells. – Published on June 7, 2018 | Cystic Fibrosis Foundation® News A new […]

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HOPE-1 Clinical Trial for SPX-101 Is Enrolling CF Patients in Canada and Europe

CYSTIC FIBROSIS NEWS TODAY by Ana Belo Van Wijk, PhD – The first patient has been enrolled and dosed in the HOPE-1 Phase 2 clinical trial evaluating Spyryx Biosciences‘ investigational drug SPX-101 as a treatment for cystic fibrosis (CF). The HOPE-1 study (NCT03229252) will take place in Alberta and Ontario in Canada, the United Kingdom, France, and Portugal. […]

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Cystic Fibrosis News Today: Spyryx CEO Talks of Potential of CF Treatment Now Entering Clinical Testing

In Interview, Spyryx CEO Talks of Potential of CF Treatment Now Entering Clinical Testing A preclinical study using animal models of cystic fibrosis (CF) showed that SPX-101, a treatment being developed by Spyryx Biosciences, effectively cleared lung mucus in the animals, regardless of the presence of genetic mutations that promote the development of the disease. […]

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